| 黄 欣,何晓微,唐乾利,黄许森,吴标良,曾鸿孟,刘 明,郭 满.MEBT/MEBO治疗老年WagnerⅢ级糖尿病足的临床研究[J].中国烧伤创疡杂志,2017,(1):44~47. |
| DOI： |
| 中文关键词: 原位再生医疗技术 湿润烧伤膏 创面修复 WagnerⅢ级 老年 糖尿病足 |
| 英文关键词:MEBT/MEBO Wound repair Wagner grade III The elderly Diabetic foot |
| 基金项目:2014年广西科学研究与技术开发计划项目 (项目编号: 桂科攻14124004-1-2); 2014 年广西自然科学基金面上项目 (2014GXNSFAA118135) |
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| 中文摘要: |
| 目的 观察MEBT/MEBO (moistexposedburntherapy/moistexposedburnointment, 原位再生医疗技 术) 治疗老年WagnerⅢ级糖尿病足的临床疗效? 方法 将2014年6月—2016年2月广西中医药大学第一附属医 院和右江民族医学院附属医院收治的52 例老年WagnerⅢ级糖尿病足患者随机分为MEBO (moistexposedburn ointment, 湿润烧伤膏) 组 (27例) 和rb?bFGF (重组牛碱性成纤维细胞生长因子) 组 (25例)? MEBO组患者 创面外涂MEBO治疗, rb?bFGF组患者创面外涂rb?bFGF凝胶治疗, 于治疗60d后对比两组患者创面治疗效果及 治疗前后伴随症状评分差值? 结果 治疗60d后, MEBO组患者创面明显缩小, 疼痛? 麻木等症状明显缓解, 疗 效优于rb?bFGF组, P<0??05, 差异具有统计学意义? 结论 MEBT/MEBO能够有效促进老年WagnerⅢ级糖尿病 足创面的愈合, 缓解创面疼痛? 麻木等临床症状, 改善患者生活质量, 值得临床推广应用? |
| 英文摘要: |
| 【Abstract】Objective: To observe the clinical efficacy of Moist Exposed Burn Therapy/Moist Exposed Burn Ointment (MEBT/MEBO) in the treatment of Wagner grade III diabetic foot (DF) in the elderly people. Methods: A total of 52 elderly patients with Wagner grade III diabetic foot admitted to The First Affiliated Hospital of Guangxi University of Chinese Medicine and The Affiliated Hospital of Youjiang Medical College for Nationalities between June 2014 and February 2016 were randomly divided into MEBO group (27 patients) and rb-bFGF group (25 patients). Patients in MEBO group were treated with the external application of MEBO while patients in rb-bFGF group were treated with the external application of rb-bFGF gel. The clinical efficacy and the score differences of concomitant symptoms before and after the treatment between the two groups were compared on day 60 of the treatment. Results: On day 60 of the treatment, the wound size was obviously decreased and the symptoms such as pain and numbness were remarkably relieved in MEBO group, which was superior to that in the rb-bFGF group, with statistically significant difference (P＜0.05). Conclusion: MEBT/MEBO deserves to be promoted in clinical treatment of Wagner grade III diabetic foot in the elderly population since it is effective in promoting the wound healing and relieving symptoms such as pain and numbness and improving patients’ quality of life. |
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