| 赵雅玫,陈 艳,谢 斌,吴 健.诱导膜技术在慢性难愈合创面中的应用研究进展[J].中国烧伤创疡杂志,2025,(1):9~12. |
| DOI： |
| 中文关键词: 骨水泥 抗生素骨水泥 诱导膜技术 慢性难愈合创面 综述 |
| 英文关键词:Bone cement Antibiotic bone cement Induced membrane technique Chronic refractory wounds Review |
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| 摘要点击次数: 650 |
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| 中文摘要: |
| 【摘要】 随着我国逐步步入老龄化社会以及人们生活水平的提高，因糖尿病、高血压等疾病引发的慢性难愈合创面的发生率逐渐升高。 临床常用的清创、局部生物敷料覆盖、负压封闭引流、 高压氧疗及植皮／皮瓣移植等慢性难愈合创面治疗方法的治疗效果欠佳，故探寻疗效更好的治疗方法一直是临床研究的重点。诱导膜技术是临床治疗慢性骨感染伴骨缺损常用的治疗手段，因其能够作为深部缺损组织的良好填充物暂时性覆盖创面，隔绝外界病原菌对创面的侵袭，以及不断释放抗生素防控创面感染，并促进肉芽组织生长而被逐渐应用于慢性难愈合创面的治疗，且取得了较为满意的临床疗效。基于此，本文对诱导膜技术在慢性难愈合创面中的作用机制及其应用研究进展进行了综述，以期进一步指导其在临床中的应用。 |
| 英文摘要: |
| 【Abstract】 With the gradual aging of China’s population and improvements in living standards, the incidence of chronic refractory wounds caused by diseases such as diabetes and hypertension has steadily increased. Conventional clinical treatments for chronic refractory wounds, including debridement, local biological dressings, vacuum sealing drainage, hyperbaric oxygen therapy, and skin grafting / flap transplantation, often yield suboptimal therapeutic outcomes. Therefore, exploring more effective treatment methods has become a key focus of clinical research. Induced membrane technique, commonly used in the treatment of chronic bone infections with bone defects, has gained attention for chronic refractory wound management. This technique provides a temporary covering for deep tissue defects, effectively isolating the wound from external pathogens, continuously releasing antibiotics to prevent infection, and promoting granulation tissue formation.As a result, induced membrane technique has shown promising clinical efficacy in the treatment of chronic refractorywounds. This paper reviewed the mechanism of action and research progress of induced membrane technique in chronic refractory wound management, aiming to further guide its clinical application. |
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