• 重度烧伤患者发生中心静脉导管相关性血流感染的危险因素分析
  • Risk Factors Analysis of Central Line-associated Bloodstream Infection in Patients with Severe Burns
  • 熊新娟,安 娜,陈翠云,王康康,王庆昕,皮红英.重度烧伤患者发生中心静脉导管相关性血流感染的危险因素分析[J].中国烧伤创疡杂志,2025,(1):31~33.
    DOI:
    中文关键词:  重度烧伤  中心静脉导管相关性血流感染  危险因素  Logistic 回归分析
    英文关键词:Severe burns  Central line-associated bloodstream infection  Risk factor  Logistic regression analysis
    基金项目:军队护理创新与培育专项计划 (培育) (2021HL068)
    作者单位
    熊新娟 100039 北京, 中国人民解放军医学院 2022 级护理专业 
    安 娜 250031 山东 济南, 中国人民解放军联勤保障部队第九六〇医院烧伤整形科 
    陈翠云 250031 山东 济南, 中国人民解放军联勤保障部队第九六〇医院烧伤整形科 
    王康康 250031 山东 济南, 中国人民解放军联勤保障部队第九六〇医院烧伤整形科特勤科 
    王庆昕 250031 山东 济南, 中国人民解放军联勤保障部队第九六〇医院重症监护室 (王庆昕) 
    皮红英 100853 北京, 中国人民解放军总医院卫勤训练中心 
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    中文摘要:
          【摘要】 目的 分析重度烧伤患者深静脉置管后发生中心静脉导管相关性血流感染 (CLABSI) 的相关危险因素。方法 选取2020年1月至2023年1月中国人民解放军联勤保障部队第九六〇医院收治的66例进行深静脉置管的重度烧伤患者作为研究对象, 收集患者性别、年龄、烧伤总面积、有无吸入性损伤、有无营养不良、是否使用烧伤治疗床、导管留置部位、导管留置时间、置管部位有无创面以及感染情况等相关资料, 并根据是否发生CLABSI将其分为发生组和未发生组, 分析重度烧伤患者深静脉置管后发生CLABSI的相关危险因素。 结果 66例进行深静脉置管的重度烧伤患者中17例( 25.76%)发生 CLABSI, 设为发生组;49 例 ( 74.24%)未发生CLABSI, 设为未发生组。发生组有营养不良、导管留置部位为股静脉、置管部位有创面的患者明显多于未发生组 (χ2 = 8.848、16.903、5.126, P= 0.003、P<0.001、P= 0.024)。多因素 Logistic 回归分析结果显示, 有营养不良、导管留置部位为股静脉是重度烧伤患者深静脉置管后发生 CLABSI 的独立危险性因素 ( 95% CI为1.233 ~23.741、0.015~ 0.435, P = 0.025、0.003)? 结论 营养状态、导管留置部位与重度烧伤患者深静脉置管后CLABSI的发生密切相关。
    英文摘要:
          【Abstract】 Objective To analyze the risk factors for central line-associated bloodstream infection (CLABSI) in patients with severe burns. Methods 66 patients with severe burns who underwent deep venous catheter admitted to No.960 Hospital of the PLA Joint Logistics Support Force from January 2020 to January 2023 were selected as the research subjects. Data of these subjects were collected including sex, age, total burned surface area, inhalation injury, malnutri-tion, application of burn treatment bed, catheter indwelling site and time, wound at catheterization site, and infection occurrence. Patients were divided into the occurrence group and the non-occurrence group according to whether CLABSI occurred to analyze the risk factors of CLABSI in severe burns patients after deep venous catheter. Results Of 66 patients with severe burns who underwent deep venous catheter, 17 cases (25.76%) suffered CLABSI, being set as the occurrence group; and the other 49 cases (74.24%) did not develop CLABSI, being set as the non-occurrence group. The patients with malnutrition, femoral vein indwelling catheter site, and wound at the catheter site in the occurrence group were significantly more than those in the non-occurrence group (χ2 = 8.848, 16.903 and 5.126, P = 0.003, P< 0.001, P = 0.024). The results of multivariate Logistic regression analysis showed that malnutrition and femoral vein indwelling site of catheter were the independent risk factors for the occurrence of CLABSI in patients with severe burns after deep venous catheter (95%CI:1.233-23.741, 0.015 - 0.435, P = 0.025 and 0.003). Conclusion Nutritional status and catheter retention site are closely related to the occurrence of CLABSI after deep venous catheter in patients with severe burns.