| 王 芳,张保龙,齐欢欢,牛婷婷.股骨颈骨折空心螺钉内固定术后供养血管注射富血小板血浆效果分析[J].中国烧伤创疡杂志,2025,(1):67~71. |
| DOI： |
| 中文关键词: 股骨颈骨折 空心螺钉内固定 富血小板血浆 髋关节功能 骨痂生长 |
| 英文关键词:Femoral neck fracture Cannulated screw internal fixation Platelet rich plasma Hip joint function Callus growth |
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| 中文摘要: |
| 【摘要】 目的 分析股骨颈骨折空心螺钉内固定术后供养血管注射富血小板血浆 (PRP) 的临床效果。方法 选取 2019 年 6 月至 2021 年 6 月郑州人民医院收治的 106 例股骨颈骨折患者作为研究对象, 按照空心螺钉内固定术后供养血管是否注射 PRP 将其分为试验组 (53例) 和对照组 (53例)。试验组患者空心螺钉内固定术后于供养血管注射 PRP, 对照组患者空心螺钉内固定术后不做处理, 对比观察两组患者围手术期指标、 骨折愈合时间、髋关节功能、骨痂生长情况以及不良事件发生情况。结果 试验组患者手术时间明显长于对照组 (t = 16.915,P<0.001), 完全负重所需时间、 骨折愈合时间均明显短于对照组 (t = 12.610、 8.213, P 均<0.001), 术中出血量与对照组无明显差异 (t = 1.685, P= 0.095); 术后 1、 3、6 个月, 试验组患者 Harris 评分、 Fernandez-Esteve骨痂评分均明显高于对照组 (术后 1 个月: t = 8.919、 6.118, P 均<0.001; 术后 3 个月: t = 10.951、 9.217, P均<0.001; 术后 6 个月: t = 7.024、 6.937, P 均<0.001); 试验组患者术后不良事件发生率为 9.43%, 明显低于对照组患者的不良事件发生率 30.19% ( χ2 = 7.185, P = 0.007)。结论 与单纯采用空心螺钉内固定治疗相比, 于空心螺钉内固定术后给予供养血管注射 PRP 治疗股骨颈骨折, 能够有效促进骨痂生长, 明显缩短完全负重所需时间及骨折愈合时间, 改善髋关节功能, 减少股骨头坏死等不良事件的发生, 临床应用价值更高。 |
| 英文摘要: |
| 【Abstract】 Objective To analyze the clinical efficacy of platelet rich plasma (PRP) injection into feeding vessels after cannulated screw internal fixation for femoral neck fracture. Methods 106 patients with femoral neck fracture admitted to Zhengzhou People’s Hospital from June 2019 to June 2021 were enrolled as research subjects. Based on whether PRP was injected into feeding vessels after cannulated screw internal fixation, the patients were divided into the experiment group (n = 53) and the control group ( n = 53). Patients in the experiment group were given PRP injection into feeding vessels after the cannulated screw internal fixation, whereas patients were left untreated after the cannulated screw internal fixation in the control group. Perioperative indicators, fracture healing time, hip joint function, callus growth, and occurrence of adverse events were compared between the two groups. Results The operation time of patients in the experiment group was significantly longer than that in the control group (t = 16.915, P<0.001), and full weight-bearing time and fracture healing time of patients were significantly shorter in the experiment group (t = 12.610 and 8.213, both P<0.001), but there was no significant difference in intraoperative blood loss volume between the two groups ( t = 1.685, P = 0.095). Respectively at month 1, 3 and 6 after operation, the Harris score and Fernandez-Esteve callus score of patients were significantly higher in the experiment group compared with the control group ( month 1 after operation: t = 8.919 and 6.118, both P< 0.001; month 3 after operation: t = 10.951 and 9.217, both P<0.001; month 6 after operation: t = 7.024 and 6.937, both P<0.001). The incidence of postoperative adverse reactions of patients in the experiment group was 9.43%, being much lower than 30.19% in the control group (χ2 = 7.185, P = 0.007). Conclusion Compared with the simple application of the cannulated screw internal fixation in the treatment of femoral neck fracture, the additional application of PRP injection into feeding vessels after the cannulated screw internal fixation can effectively promote the callus growth, significantly shorten the full weight-bearing time and fracture healing time, improve hip joint function, reduce the occurrence of femoral head necrosis and other adverse reactions, and realize better clinical efficacy. |
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