| 程如金,尹闪闪.儿童幽门螺杆菌感染性消化性溃疡相关危险因素分析[J].中国烧伤创疡杂志,2025,(1):75~78. |
| DOI： |
| 中文关键词: 儿童 消化性溃疡 幽门螺杆菌感染 危险因素 Logistic 回归分析 |
| 英文关键词:Children Peptic ulcer Helicobacter pylori infection Risk factors Logistic regression analysis |
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| 中文摘要: |
| 【摘要】 目的 探讨分析儿童幽门螺杆菌感染性消化性溃疡的相关危险因素。 方法 选取 2021 年 2 月至2023 年 2 月南阳市中心医院收治的 73 例消化性溃疡患儿作为研究对象, 收集患儿性别、年龄、家族史、饮食结构、生活习惯、有无非甾体类抗炎药应用史、有无心理障碍、幽门螺杆菌感染情况等相关资料, 根据是否感染幽门螺杆菌将其分为感染组和非感染组, 分析消化性溃疡患儿存在幽门螺杆菌感染的相关危险因素。 结果 73 例消化性溃疡患儿中 51 例 (69.86%) 感染幽门螺杆菌, 设为感染组; 22 例 (30.14%) 未感染幽门螺杆菌, 设为非感染组。 多因素 Logistic 回归分析结果显示, 性别为男性、年龄≥6 岁、有家族史、经常吃外卖、偏爱酸辣、偏爱冷食、住校/小餐桌、有非甾体类抗炎药应用史、有心理障碍是消化性溃疡患儿存在幽门螺杆菌感染的独立危险因素 (95% CI 为 1.155 ~ 1.771、1.027 ~ 2.539、1.660 ~ 224.735、1.028 ~ 11.010、1.114 ~ 2.499、1.015 ~5.162、2.864 ~ 145.463、1.289 ~ 15.651、1.024 ~ 1.569, P = 0.001、0.038、0.018、0.045、0.012、0.046、0.003、0.018、0.029)。结论 性别、年龄、有无家族史、是否经常吃外卖、是否偏爱酸辣、是否偏爱冷食、是否住校/小餐桌、有无非甾体类抗炎药应用史、有无心理障碍是儿童幽门螺杆菌感染性消化性溃疡的独立影响因素。 |
| 英文摘要: |
| 【Abstract】 Objective To analyze the risk factors for helicobacter pylori positive peptic ulcer in children.Methods 73 children with peptic ulcers, admitted to Nanyang Central Hospital between February 2021 and February 2023, were selected as research subjects. Data were collected including sex, age, family history, dietary structure, living habits, history of application of non-steroidal anti-inflammatory drug, psychological disorders, and helicobacter pylori infec-
tion. Patients were divided into the infection group and the non-infection group based on the occurrence of helicobacter pylori infection. The risk factors of helicobacter pylori infection in children with peptic ulcer were analyzed. Results 51 (69.86%) of the 73 children patients with peptic ulcer developed helicobacter pylori infection, which were set as the infection group, while the other 22 (30.14%) children patients without developing helicobacter pylori infection were set as the non-infection group. The results of multivariate Logistic regression analysis showed that male children with age ≥6 years,family history, frequent takeaways diet, hot and sour taste preference, cold food preference, boarding in at the school or dining at small dining tables, history of application of non-steroidal anti-inflammatory drug, and psychological disorders were the independent risk factors for helicobacter pylori infection in children with peptic ulcers (95%CI: 1.155-1.771, 1.027-2.539, 1.660-224.735, 1.028-11.010, 1.114-2.499, 1.015-5.162, 2.864-145.463, 1.289-15.651, 1.024-1.569,P= 0.001, 0.038, 0.018, 0.045, 0.012, 0.046, 0.003, 0.018 and 0.029). Conclusion Sex, age, family history, frequent takeaways diet, hot and sour taste preference, cold food preference, boarding in at the school or dining at small dining tables, history of application of non-steroidal anti-inflammatory drug, and psychological disorders were independent risk factors for helicobacter pylori infection in children with peptic ulcers. |
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