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| DOI： |
| 中文关键词: 胃修补术，胃溃疡，胃穿孔，气腹压力，胃肠激素，炎症 |
| 英文关键词:Keywords: gastric repair surgery, gastric ulcer, gastric perforation, pneumoperitoneum pressure, gastrointestinal hormones, inflammation |
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| 中文摘要: |
| 对比分析不同气腹压力腹腔镜胃修补术在胃溃疡穿孔中的应用疗效。方法：选取2021年6月～2023年6月收治的80例胃溃疡穿孔患者为研究对象，分为高压力组（40例）与低压力组（40例），高压力组患者行腹腔镜胃修补术过程中将气腹压力设置为15 mmHg，低压力组患者行行腹腔镜胃修补术过程中将气腹压力设置为12 mmHg，对比应用疗效。结果：低压力组患者术中出血量及手术时间与高压力组无明显差异（P均＞0.05），而肠鸣音恢复时间、术后排气时间、住院时间短于高压力组（P＜0.05）；术后5 d，低压力组患者MTL、PGⅡ、PGⅠ、GAS水平均高于高压力组（P＜0.05）；术后5 d，低压力组患者CRP、PGE2、IL-8水平均低于高压力组（P＜0.05）；低压力组患者并发症总发生率少于高压力组（P＜0.05）。 |
| 英文摘要: |
| Objective: To compare and analyze the therapeutic effects of laparoscopic gastric repair under different pneumoperitoneum pressures in the treatment of gastric ulcer perforation. Method: 80 patients with gastric ulcer perforation admitted from June 2021 to June 2023 were selected as the research subjects and divided into a high pressure group (40 cases) and a low pressure group (40 cases). During laparoscopic gastric repair surgery, the pneumoperitoneum pressure was set to 15 mmHg in the high pressure group, and 12 mmHg in the low pressure group. The therapeutic effects were compared. Result: There was no significant difference in intraoperative bleeding and surgical time between the low-pressure group and the high-pressure group (P>0.05), while the recovery time of bowel sounds, postoperative exhaust time, and hospitalization time were shorter in the low-pressure group than in the high-pressure group (P<0.05); Five days after surgery, the levels of MTL, PG Ⅱ, PG Ⅰ, and GAS in the low pressure group were higher than those in the high pressure group (P<0.05); Five days after surgery, the average levels of CRP, PGE2, and IL-8 in the low-pressure group were lower than those in the high-pressure group (P<0.05); The total incidence of complications in the low-pressure group was lower than that in the high-pressure group (P<0.05). Conclusion: Setting the pneumoperitoneum pressure at a relatively low level during laparoscopic gastric repair surgery for patients with gastric ulcer perforation can ensure the smooth progress of the surgery, reduce damage to the patient, alleviate postoperative inflammatory reactions, facilitate the recovery of gastrointestinal function, and reduce the risk of complications. |
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