• 连续性血液净化联合异甘草酸镁治疗烧伤脓毒症效果分析
  • Analysis of the effect of continuous blood purification combined with magnesium isoglycyrrhizinate in the treatment of burn sepsis
  • DOI:
    中文关键词:  连续性血液净化  异甘草酸镁  烧伤  脓毒症  炎症反应  免疫功能  疾病严重程度
    英文关键词:Continuous blood purification  Magnesium isoglycyrrhizinate  burn  Sepsis  Inflammatory response  immunity  Disease severity
    基金项目:
    作者单位邮编
    林美霞* 商丘市第一人民医院 476100
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    中文摘要:
          分析连续性血液净化联合异甘草酸镁治疗烧伤脓毒症的效果。方法 选取2020年6月-2024年6月收治的40例烧伤脓毒症患者为研究对象,进行连续性血液净化联合异甘草酸镁治疗,观察NLR、IL-6、降钙素原、CRP等炎症反应指标,IgG、IgM、IgA等免疫功能指标、疾病严重程度(SOFA评分)。结果 治疗第24、48、72小时时,NLR、白细胞介素-6、降钙素原、C反应蛋白水平明显低于治疗前(P<0.05),IgG、IgM、IgA水平高于治疗前(P<0.05),SOFA评分低于治疗前(P<0.05)。结论 连续性血液净化联合异甘草酸镁治疗烧伤脓毒症,有利于降低患者炎症反应程度,提高患者免疫功能,改善病情严重程度。
    英文摘要:
          Analyze the efficacy of continuous blood purification combined with magnesium isoglycyrrhizinate in the treatment of burn sepsis. Method: Forty patients with burn sepsis admitted from June 2020 to June 2024 were selected as the research subjects. Continuous blood purification combined with magnesium isoglycyrrhizinate treatment was performed, and inflammatory response indicators such as NLR, IL-6, procalcitonin, CRP, immune function indicators such as IgG, IgM, IgA, and disease severity (SOFA score) were observed. At 24, 48, and 72 hours of treatment, NLR、 The levels of interleukin-6, procalcitonin, and C-reactive protein were significantly lower than before treatment (P<0.05), while the levels of IgG, IgM, and IgA were higher than before treatment (P<0.05). The SOFA score was lower than before treatment (P<0.05). Conclusion: Continuous blood purification combined with magnesium isoglycyrrhizinate is beneficial for reducing the degree of inflammatory response, improving immune function, and alleviating the severity of burn sepsis in patients.